prodrug
Inactive Drug Activated by the Body
Plain-language definition
A medication given in an inactive form that the body converts into the active drug, often to improve absorption or reduce side effects. Many glaucoma drops - such as latanoprost - are prodrugs activated by enzymes in the cornea.
Where this term comes up
“It's a prodrug that becomes active after penetrating the eye.”
Medication · Ilevro (Nepafenac 0.3%)
“It is the prodrug of acyclovir - converted to acyclovir in the body - and offers better oral bioavailability and less frequent dosing than acyclovir itself.”
Medication · Valacyclovir (Valtrex)
“IV ganciclovir or oral valganciclovir (the prodrug converted to ganciclovir in the body) is used systemically for cytomegalovirus disease in immunocompromised patients.”
Medication · Ganciclovir Gel (Zirgan)
- Category
- Medication
- Also written as
- prodrugs
Medication terms describe drugs or drug classes that may be used in eye care, neurology, inflammation, infection, or pain treatment.
Related glossary terms
- acyclovir
Herpes Antiviral
- antiviral
Virus-Fighting Drug
- trifluridine
Antiviral Eye Drop
- cornea
Clear Front Window
- epithelium
Surface Cell Layer
- immunocompromised
Weakened Immune System
A note on medical context
A glossary definition can explain a word, but it cannot tell you whether a symptom or test result is serious. If this term came from an article, use the full article and your clinician's guidance for context.