MOGAD
MOG Antibody Disease
Plain-language definition
An autoimmune condition caused by antibodies against MOG protein. Can cause optic neuritis with often good recovery but relapse risk.
Read our full article on MOGAD (MOG Antibody Disease).
Where this term comes up
“Optic neuritis raises two separate questions: how the current eye episode should be treated, and whether the pattern suggests multiple sclerosis (MS), MOGAD, NMO, infection, inflammation, or another cause.”
Guide · Optic Neuritis and MS Risk - Understanding Your Diagnosis
“for NMOSD, MOGAD, and myasthenia gravis”
Medication · Rituximab (Rituxan)
“Associated with MOGAD”
Test · Autoantibody Testing Panels
- Category
- Condition, finding, or disease process
- Also written as
- No alternate forms listed.
Pathology terms describe diseases, tissue changes, exam findings, or complications that can affect vision or eye comfort.
Related glossary terms
- NMO
Neuromyelitis Optica
- autoimmune
Self-Attacking Immune Response
- AQP4
Aquaporin-4
- MOG
Myelin Oligodendrocyte Glycoprotein
- MRI
Magnetic Resonance Imaging
- complement
Immune Defense Cascade
A note on medical context
A glossary definition can explain a word, but it cannot tell you whether a symptom or test result is serious. If this term came from an article, use the full article and your clinician's guidance for context.