MOG
Myelin Oligodendrocyte Glycoprotein
Plain-language definition
A protein on myelin sheaths in the CNS. Antibodies against MOG cause optic neuritis and other inflammatory conditions (MOGAD).
Where this term comes up
“MOG antibody disease (MOGAD) is an autoimmune inflammatory condition affecting the central nervous system.”
Condition · MOGAD (MOG Antibody Disease)
“MOG antibodies”
Test · Autoantibody Testing Panels
“MOG antibody disease (MOGAD) - off-label, usually for relapsing or severe disease”
Medication · Rituximab (Rituxan)
- Category
- Immune system term
- Also written as
- No alternate forms listed.
Immunology terms describe immune-system activity, antibodies, inflammation, or autoimmune processes that can affect the eyes and nerves.
Related glossary terms
- AQP4
Aquaporin-4
- MOGAD
MOG Antibody Disease
- NMO
Neuromyelitis Optica
- MRI
Magnetic Resonance Imaging
- autoimmune
Self-Attacking Immune Response
- bilaterally
On Both Sides
A note on medical context
A glossary definition can explain a word, but it cannot tell you whether a symptom or test result is serious. If this term came from an article, use the full article and your clinician's guidance for context.