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NMO

Neuromyelitis Optica

Plain-language definition

An autoimmune disorder attacking the optic nerves and spinal cord, associated with AQP4 antibodies. Requires different treatment than MS.

Where this term comes up

  • Optic neuritis raises two separate questions: how the current eye episode should be treated, and whether the pattern suggests multiple sclerosis (MS), MOGAD, NMO, infection, inflammation, or another cause.

    Guide · Optic Neuritis and MS Risk - Understanding Your Diagnosis

  • It's commonly used for acute optic neuritis, NMO attacks, and other severe inflammatory conditions.

    Medication · Methylprednisolone (IV Steroids)

  • MS-related optic neuritis, neuromyelitis optica (NMO), MOG antibody disease, infection, and other inflammatory diseases can differ substantially in prognosis and treatment.

    Condition · Optic Neuritis

Category
Condition, finding, or disease process
Also written as
No alternate forms listed.

Pathology terms describe diseases, tissue changes, exam findings, or complications that can affect vision or eye comfort.

Related glossary terms

  • MOGAD

    MOG Antibody Disease

  • autoimmune

    Self-Attacking Immune Response

  • MRI

    Magnetic Resonance Imaging

  • AQP4

    Aquaporin-4

  • MOG

    Myelin Oligodendrocyte Glycoprotein

  • thinning

    Tissue Loss

A note on medical context

A glossary definition can explain a word, but it cannot tell you whether a symptom or test result is serious. If this term came from an article, use the full article and your clinician's guidance for context.