neurosyphilis
Syphilis of the Nervous System
Plain-language definition
Syphilis infection affecting the brain, spinal cord, or nerves. Can cause pupil abnormalities (Argyll Robertson pupils), optic atrophy, and vision loss.
Where this term comes up
“This pattern, called "light-near dissociation," is historically associated with neurosyphilis but can occur with other conditions affecting the brainstem.”
Condition · Argyll Robertson Pupils
“Originally described in tertiary syphilis (neurosyphilis), Argyll Robertson or Argyll Robertson-like pupils can also be reported in other diseases - including diabetes mellitus and multiple sclerosis.”
Finding · Light-Near Dissociation
“Argyll Robertson pupils are small, irregular pupils that show light-near dissociation, a classic but now uncommon finding associated with neurosyphilis.”
Finding · Anisocoria (Unequal Pupils)
- Category
- Condition, finding, or disease process
- Also written as
- No alternate forms listed.
Pathology terms describe diseases, tissue changes, exam findings, or complications that can affect vision or eye comfort.
Related glossary terms
- syphilis
Systemic Bacterial Infection
- MRI
Magnetic Resonance Imaging
- aneurysm
Vessel Bulge
- anisocoria
Pupils of Unequal Size
- apraclonidine
Alpha-Agonist Eye Drop
- bilaterally
On Both Sides
A note on medical context
A glossary definition can explain a word, but it cannot tell you whether a symptom or test result is serious. If this term came from an article, use the full article and your clinician's guidance for context.