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neurosyphilis

Syphilis of the Nervous System

Plain-language definition

Syphilis infection affecting the brain, spinal cord, or nerves. Can cause pupil abnormalities (Argyll Robertson pupils), optic atrophy, and vision loss.

Where this term comes up

  • This pattern, called "light-near dissociation," is historically associated with neurosyphilis but can occur with other conditions affecting the brainstem.

    Condition · Argyll Robertson Pupils

  • Originally described in tertiary syphilis (neurosyphilis), Argyll Robertson or Argyll Robertson-like pupils can also be reported in other diseases - including diabetes mellitus and multiple sclerosis.

    Finding · Light-Near Dissociation

  • Syphilis: Penicillin (neurosyphilis protocol if CNS involved)

    Condition · Optic Perineuritis

Category
Condition, finding, or disease process
Also written as
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Pathology terms describe diseases, tissue changes, exam findings, or complications that can affect vision or eye comfort.

Related glossary terms

A note on medical context

A glossary definition can explain a word, but it cannot tell you whether a symptom or test result is serious. If this term came from an article, use the full article and your clinician's guidance for context.